Charles University in Prague, Faculty of Science, Department of Inorganic Chemistry
This project is aimed at developing student's practical synthetic skill through the synthesis of several ferrocene derivatives suitable for further organometallic synthesis, namely acetylferrocene, ethynylferrocene, ferrocenecarboxylic acid and possibly also other compounds. All compounds prepared are supposed to be characterized by conventional analytical methods (NMR and IR spectroscopy).
Charles University in Prague, Faculty of Science, Department of Inorganic Chemistry
This project is focused on preparation and basic characterization of novel crystalline materials based on hydrogen-bonded salts and cocrystals of selected organic bases. The student will prepare new compounds via isothermal crystallization (polar solvents) and characterize them by spectroscopic (IR, Raman and UV/VIS spectroscopy) and diffraction methods (powder and single crystal X-ray diffraction) within the project. Finally, linear and non-liner optical properties of the materials will be studied.
Charles University in Prague, Faculty of Science, Department of Analytical Chemistry
Research in the field of modern electroanalytical chemistry. There are no special prerequisites. Staff members of UNESCO Laboratory of electroanalytical chemistry have long time experience in this field so that no preliminary background in electroanalytical techniques is requested. The department has close cooperation with Heyrovsky institute of physical chemistry of the Academy of Sciences of the Czech Republic and electroanalytical chemistry has a long tradition in the Czech Republic since the discovery of polarography by Professor Heyrovsky. Moreover, we the department has long-time cooperation with several Brazilian research institutions (FIOCRUZ etc.) and with several Brazilian universities. The exact research project will be prepared in cooperation with prospective visitor as far as the technique, analyte, matrix etc. are concerned. The laboratory is well equipped with modern electroanalytical instrumentation, HPLC systems with electrochemical detection, FIA systems with electrochemical detection etc. The staff pays attention to the determination of environmental carcinogens, ecotoxic substance, pesticides, anticancer drugs and other biologically active organic substances using different electroanalytical techniques, non-traditional electrodes, new-type of electrochemical sensors etc.
Charles University in Prague, Faculty of Science, Department of Organic and Nuclear Chemistry
Description: Our group is currently engaged in several projects that encompass different areas of organic chemistry involving transition metal compound catalysis such (C-C bond activation, [2+2+2]cyclotrimerizations, cross-metathesis), Lewis base organocatalysis, synthesis of natural compounds (estrone) and biologically active substances (ligands for estrogenic receptors), ferrocene and carborane chemistry.
Charles University in Prague, Faculty of Science, Department of Organic and Nuclear Chemistry
Description: the aim of our laboratory is to develop a fully synthetic platform for the discovery of novel functional miniproteins. The class of naturally occurring cysteine-rich miniproteins is structurally and functionally extremely diverse. Synthetic combinatorial libraries posses a great potential to explore the functional sequence space of the cysteine-rich miniproteins. The synthetic nature of the miniprotein libraries will enable to screen for unprecedented functions and promises to have a major impact in the development of new catalysts, molecular probes, biomarkers and therapeutics.
Charles University in Prague, Faculty of Science, Department of Organic and Nuclear Chemistry
Description: the research program in our laboratory is focused on the development of new synthetic methods for the preparation of enantiomerically pure compounds from simple and readily available starting materials using catalysis by small organic molecules. Our aim is not only to develop new methods but also application of our developed protocols for the preparation of biologically active substances.
Charles University in Prague, Faculty of Science, Department of Organic and Nuclear Chemistry
Description: novel types of modified derivatives and analogues of nucleobases, nucleosides, nucleotides and nucleic acids are designed and prepared for applications in all areas of biomedicinal sciences (medicinal chemistry, biochemistry, chemical biology, bioanalysis etc.).
Charles University in Prague, Faculty of Science, Department of Organic and Nuclear Chemistry
Description: our reseach focuses on the study of the fate of organic compounds infiltrating into the ecosystem and on the means of their removal by plant biotechnology (phytoremediation). The studied compounds are mainly pharmaceuticals and their metabolites, or organic compounds from consumer products chemistry. Another field of our research is the synthesis of radiolabeled compounds for metabolic experiments and radiopharmaceuticals.
Charles University in Prague, Faculty of Science, Department of Organic and Nuclear Chemistry
Description: research program of the laboratory is focused on studying elementary steps in organic and organometallic reactions using mass spectrometry, ion spectroscopy and quantum chemistry. The aim is a deeper understanding of reaction mechanisms and formulation of new general concepts in organic and organometallic reactivity
Charles University in Prague, Faculty of Science, Department of Organic and Nuclear Chemistry
Description: research interest of the group lies in the field of organic synthesis. Currently, we are studying methods for enantioselective preparation of quaternary carbon stereocentres with the expected application to the synthesis of biologically active natural products and their derivatives.
Charles University in Prague, Faculty of Science, Department of Organic and Nuclear Chemistry
Description: group of Supramolecular Chemistry works mainly on development of the new methods for synthesis of cyclodextrin derivatives and on utilization of these derivatives in practical applications.
Research Center of Membrane Processes, Stráž pod Ralskem
- characterization of selective properties of different types of membranes (IM, MF, IM with high porosity, different structures IM, etc.)
- determining which of the membranes is more selective to monovalent ions, which on the other hand is not selective at all, etc. All this in relation to the structure of the IM / MF
- determination of the possibility of further modifications IM in order to improve their selective properties