Topic Overview:

Electroanalytical monitoring of biological active compounds (drugs, pollutants, biomarkers, food contaminants,  etc.)

Task:

Literature search and development of new electroanalytical methods.

Requirements:

Basic knowledge of electroanalytical methods.

Outcomes:

Publication.
Charles University in Prague, Faculty of Science, Department of Analytical Chemistry
Electroanalytical Monitoring of Biological Active Compounds
UNIGOU REMOTE - AVAILABLE TOPICS
Topic Overview:

Soil organic matter, in a narrower sense, humic substances, has been subject of research for several centuries. Nevertheless, questions on its formation or character still have not been resolved. The traditional polymer theory seems to be replaced in the last two decades by supramolecular views, lately claims on the non-existence of the humic substances have become rampant, looking at the soil organic matter as a complex mixture of products at various degrees of the decomposition of decaying original plant or animal matter. Plants exude a mucous substance through their roots which can also contrbute to soil organic matter or soil solution.

Task:

Literature search on current knowledge on plant root mucus....). The search will focus on mucus compositon, including water and organics/inorganics contents, and, if available, mucus rheological or diffusion properties. An overview of papers will be written, the number of papers is not predetermined and will depend on student’s abilities

Requirements:

Basic knowledge of organic and colloid chemistry, some knowledge of soil or plant chemistry advantageous, access to some scientific database (SciFinder, Web of Science etc.).

Outcomes:

Final report on results including the overview described above.

References:

Advices will be provided at the beginning of the internship. Meantime, Web of Science or SciFinder can be consulted with keywords like root mucs AND (composition OR rheology OR diffusion).
Brno University of Technology, Faculty of Chemistry, Materials Research Centre – Laboratory of Biocolloids
Plant Root Mucus as an Input to Soil Organic Matter
Topic Overview:

Extracellular matrix is environment surroundning cells in tissues etc. Tissue engineering, drug delivery, cell cultivation and similar bioapplications calls for suitable models of the extracellular matrix. These models serve in development of, e.g., scaffolds for tissue engineering or drug delivery systems. Hydrogels can serve as suitable models due to their similarity to the extracellular matrix.

Task:

Literature search on recent advances (last one-two years) in hydrogels for mimicking the extracellular matrix in various application fields. Hydrogels based on biopolymers (polysaccharides, proteins) should be preferred. An overview of papers will be written (final report), the number of papers is not  predetermined and will depend on student’s abilities and interests.

Requirements:

Basic knowledge of biopolymer and/or colloid chemistry, access to some scientific database (SciFinder, Web of Science etc.).

Outcomes:

Final report on results including the overview described above.

References:

Advices will be provided at the beginning of the internship. Meantime, Web of Science or SciFinder can be consulted with keywords like hydrogel AND (ECM mimics).

Notes:

ECM = common abbreviation for “extracellular matrix”.
Brno University of Technology, Faculty of Chemistry, Materials Research Centre – Laboratory of Biocolloids
Hydrogel Mimics of Extracellular Matrix
Topic Overview:

Soil organic matter, in a narrower sense, humic substances, has been subject of research for several centuries. Nevertheless, questions on its formation or character still have not been resolved. The traditional polymer theory seems to be replaced in the last two decades by supramolecular views, lately claims on the non-existence of the humic substances have become rampant, looking at the soil organic matter as a complex mixture of products at various degrees of the decomposition of decaying original plant or animal matter. Further, it can contain also metabolic products of the soil microorganisms.

Task:

Literature search on the synthesis of polyketides in soil, thermodynamics and kinetics of synthesis reactions.   Preparation of base to discuss their potential incorporation into the principal structural unit of the soil organic matter.

Requirements:

Basic knowledge of physical and organic chemistry. Experience with natural organic matter, soil chemistry, humic substances is advantageous but not required.

Outcomes:

Final report on results.

References:

An example of basic reference:
M.Schnitzer, C.M.Monreal. Quo Vadis Soil Organic Matter Research?: A Biological Link to the Chemistry of Humification. Advances in Agronomy 113, pp. 139-213 (2011) .
Brno University of Technology, Faculty of Chemistry, Materials Research Centre – Laboratory of Biocolloids
A Physico-Chemical Contribution to Discussion on Soil Organic Matter
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